Posts

Your mineral water may be the cure to constipation!

Image
Constipation advice usually starts with the same tired line: “just eat more fiber.” Yet millions of people follow that guidance and still feel bloated, uncomfortable, and stuck. New research from King’s College London suggests it is time to rethink the standard script—and look instead at some surprisingly specific foods and supplements that actually move the needle on chronic constipation. Before reaching for laxatives, take a closer look at your mineral water. Kiwi, rye, and mineral water to the rescue For the first time, scientists have pulled together rigorous, evidence‑based dietary guidelines focused solely on adults with long‑term constipation. After analyzing more than 75 clinical trials, the team found that three everyday options consistently stood out: kiwifruit, rye bread, and mineral‑rich water . People who added 2–3 kiwis a day, swapped white bread for rye, or drank high‑mineral waters—especially those rich in magnesium and sulfates—often reported more frequent, softer, and...

LARPs in treatment of Fibrosis

Image
LARPs or La- related proteins, are a superfamily of proteins present on both plants and animals. What is LARP6? LARP6 is a crucial RNA-binding protein. The key function of this particular protein is it regulates type I collagen synthesis by binding to the 5’ stem-loop structure on collagen mRNAs. Histology findings of skin biopsy showing extensive fibrosis with dense subepithelial collagen deposition, sparse inflammatory cell infiltration (black arrow), and entrapment of the dermal adnexa between the collagen fibers (white arrow) (a, b). Atrophy of the epidermis and loss of epidermal papilla (c) (H&E stain ×10). Ref. Nakalema G, Egesa WI, Kumbakulu PK, et al. Sclerema neonatorum in a term infant: a case report and literature review. Case Rep Pediatr. 2020;2020:8837064. https://doi.org/10.1155/2020/8837064. Researchers at Florida State University’s Institute of Molecular Biophysics and Department of Chemistry and Biochemistry have uncovered how a protein in the human  body ...

How vitamin D might slow aging

Image
Vitamin D, the familiar   “sunshine vitamin,”   is stepping into the spotlight for a very different reason: it may help slow cellular aging from the inside out. A new analysis of a large clinical trial suggests that daily vitamin D supplements can protect tiny structures on our DNA called telomeres, which are closely tied to how fast our cells, and ultimately our bodies, grow old. Vitamin D or cholecalciferol, known as "sunshine vitamin" might help slow down cellular aging Photo by Vitolda Klein on Unsplash How vitamin D might slow aging Telomeres sit at the ends of chromosomes like the plastic tips on shoelaces, shielding our genetic material each time a cell divides. As the years pass, these caps naturally shorten; when they become too short, cells stop dividing properly and are more likely to malfunction or die, raising the risk of diseases such as cancer, heart disease, and osteoarthritis. In the VITAL trial, researchers followed 1,031 older adults for four years and fou...

What really is PCOD and PCOS? All you need to know

Image
Nutritional Modulation of Polycystic Ovary Syndrome (PCOS): A Metabolic and Hormonal Perspective A representation of the symptomatic exhibition Credits: Dr. Manisha Jain Abstract Polycystic Ovary Syndrome (PCOS) is a complex endocrine–metabolic disorder characterized by hormonal imbalance, insulin resistance, and chronic low-grade inflammation. Emerging evidence highlights nutrition as a primary, non-pharmacological intervention capable of restoring metabolic homeostasis. This blog presents a structured, scientific overview of how dietary composition influences PCOS pathophysiology, emphasizing glycemic control, macronutrient optimization, anti-inflammatory strategies, and sustainable lifestyle integration. 1. Understanding PCOS as a Metabolic-Endocrine Disorder 1.1 Definition and Prevalence PCOS affects women of reproductive age and manifests through: Oligo- or anovulation Hyperandrogenism Polycystic ovarian morphology Beyond reproductive...