The microbiome in cancer immunotherapy

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Laurence Zitvogel, Nicola Segata, Jonathan Peled and Maria Rescigno 

Abstract

Simple Summary

The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies

Cancer immunotherapy is a treatment modality that involves the stimulation of the patient’s immune system to fight off tumors. Although efficient in limiting the disease progression of several solid tumors, including lung cancer and melanoma, some patients may have poor outcomes. This review focuses on the role of the gut microbiota (the microbial community residing in the gastrointestinal tract) in immunity and cancer immunotherapy. Manipulation of the gut microbiota with dietary interventions or fecal microbiota transplantation to enhance response to immunotherapy could pave the way for personalized therapies with improved efficacy.

Chaired by Luca Danelli

The microbiota can influence the immune system and modulate response to cancer immunotherapy. In this webinar, our speakers will introduce the role of the microbiome in cancer immunotherapy, discussing recent developments in the field. The presentations will be followed by a panel discussion and Q&A session. The webinar will be hosted by Nature Cancer and Nature Communications editors.

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