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Showing posts from September, 2025

Fat Loss Without the Lies: What Really Works and Why

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Fat loss is often surrounded by myths, shortcuts, and confusion. But the truth is simple: losing fat is not about magic diets or secret tricks—it is about science. Backed by physiology , nutrition , and evidence-based research , fat loss can be explained logically and achieved systematically. This blog explores all aspects of fat loss—nutrition, exercise, lifestyle, hormones, and advanced methods—so you can understand and apply the most effective strategies in a study-friendly and practical way. Behind every journey of fat loss is a story of patience, small choices, and quiet victories. Photo by i yunmai on Unsplash 1. The Fundamental Law of Fat Loss At the core of fat loss lies energy balance : if you burn more calories than you consume, your body uses stored fat to fill the gap. This is a universal principle explained by the law of thermodynamics . When in a calorie deficit , stored fat undergoes lipolysis (breakdown) and is converted into usable energy, with the by-products e...

Inside the Minds of App Users: Cohort-Based Findings on Satisfaction and Innovation

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In a rapidly digitizing world, understanding how users perceive existing applications and what they expect from future solutions is essential. To capture these perspectives, a population cohort study was conducted with 31 respondents , focusing on satisfaction levels, missing applications, problem areas, and preferred communication channels. The findings provide a clear window into current trends and unmet needs in the app ecosystem. 31 voices, one message: apps must evolve. From health to education, users want more than entertainment — they want solutions. Photo by Gilles Lambert on Unsplash 1. Satisfaction with Current Apps Respondents were asked to rate their satisfaction on a scale of 1 (not satisfied at all) to 5 (highly satisfied). 1: 1 respondent 2: 6 respondents 3: 7 respondents 4: 15 respondents 5: 2 respondents Interpretation: The majority expressed being “more or less satisfied.” However, only a small percentage reported complete satisfaction. This su...

This killer fungus strikes at sunset. Here’s how

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The Sunset Zombie Fungus: A Deadly Precision No, this fungi-infected fly did not just step out of a bubble bath. The white, sudsy looking structures erupting from the insect's back are for launching fungal spores. Credit: Carolyn Elya Lab Entomophthora muscae is a parasitic fungus that transforms fruit flies into "zombies," compelling them to die at sunset. Once infected, the fungus infiltrates the fly's body, spreading to the brain and manipulating its behavior. The fly climbs to an elevated surface, attaches itself, and dies with wings extended, allowing the fungus to launch its spores into the environment. For years, scientists were puzzled by the consistent timing of the fly's death. Recent research led by Carolyn Elya at Harvard University has uncovered that the fungus possesses its own internal clock. Experiments with genetically modified flies, including those with disrupted circadian rhythms, showed that the timing of death remained unchanged, indicatin...

Measure blood sugar with a grain of salt

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Continuous glucose monitors (CGMs), once limited to diabetes care, are now being explored by healthy individuals and researchers alike. But as science reveals, interpreting their data in people without diabetes is far from straightforward Credits: Unsplash Nicole Spartano doesn’t have diabetes. Yet the Boston University epidemiologist has worn a continuous glucose monitor (CGM) from time to time. Her interest is personal and professional: she wants to understand how food, sleep, and exercise affect her blood sugar, and whether these devices could help people prevent diseases like diabetes while also improving overall health. CGMs were originally developed for people with diabetes to track blood sugar and guide insulin use. Insulin is the hormone that allows cells to absorb glucose and convert it into energy. But in people without diabetes, what CGM readings mean is still an open question. Despite that uncertainty, CGMs have surged in popularity. High-profile figures such as Casey Me...

When Menopause Comes Early, So May Diabetes

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A recent study published in JAMA Network Open has shed light on an important but often overlooked connection— how the age at which a woman reaches menopause may influence her risk of developing type 2 diabetes. Conducted among over 1,000,000 Korean women, the research found a clear link: the earlier the onset of menopause, the higher the risk of diabetes. Finger-prick testing helps track blood sugar levels, empowering people with diabetes to stay ahead of their health. Photo by isens usa on Unsplash Women who experienced menopause before the age of 40—classified as premature menopause—faced a 27% greater risk of developing type 2 diabetes compared to those who underwent menopause at 50 or older. Even those who entered menopause between ages 40 and 44 had an elevated risk. Why does this happen? Estrogen, the key hormone that declines after menopause, plays a crucial role in how the body uses insulin and regulates blood sugar. When menopause occurs earlier, the body is exposed to les...

A cold today helps keep the COVID away

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Protective Role of Rhinovirus Infections Against SARS-CoV-2: Insights into Age-Dependent Immunity Cough and cold by rhinovirus. Credit:  Photo by Andy Vult on Unsplash Introduction Adults are more likely than children to develop symptomatic and severe COVID-19. One hypothesis suggests that frequent respiratory viral infections in children prime antiviral defenses, offering protection against SARS-CoV-2. This study investigates whether prior respiratory infections, particularly rhinovirus, influence SARS-CoV-2 susceptibility and severity. Methods Within the Human Epidemiology and Response to SARS-CoV-2 cohort, 10,493 nasal swabs from 1,156 participants were analyzed for 21 respiratory pathogens. Case-cohort and case-control approaches were used. RNA sequencing was performed on 538 swabs to identify molecular mechanisms underlying observed protection. Results Participants with rhinovirus infection in the preceding 30 days had a 48% lower risk of SARS-CoV-2 infection (adjusted ...

Are Ultra-Processed Foods as Bad as We Think?

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  Colorful, convenient, and everywhere: ultra-processed snacks like chips and puffs dominate supermarket shelves, raising questions about how they shape our health. Credits: Kenishirotie/Alamy In the early 2000s, Brazilian nutrition researcher Carlos Monteiro noticed something puzzling. People were buying less sugar, salt, and oil than in past decades—yet obesity and type 2 diabetes rates were climbing. The answer came when he realized that while raw ingredients were declining, pre-packaged foods like frozen pizzas, sugary cereals, and snacks were surging. These weren’t just processed foods; they were ultra-processed foods (UPFs)—products altered so much that their original ingredients were unrecognizable. What Are UPFs? Monteiro introduced the term in 2009 through the NOVA classification system , which categorizes foods based on processing levels: Group 1: Unprocessed/minimally processed (fruits, vegetables, grains) Group 2: Processed culinary ingredients (oils, salt, sugar) Gr...

Air pollution directly linked to increased dementia risk

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Air pollution is often linked with breathing problems and heart disease. But new research led by clinician–neuroscientist Hui Chen (University of Technology Sydney) and Xiaobo Mao (Johns Hopkins University) shows it may also accelerate Lewy body dementia — a devastating condition that affects memory and movement. A study has found that exposure to air pollution can increase the risk of developing Lewy body dementia.Credit: Sonu Mehta/Hindustan Times/Shutterstock Key Findings –  What is Lewy body dementia? An umbrella term covering dementia with Lewy bodies and Parkinson’s disease dementia, caused by toxic clumps of α-synuclein proteins in brain cells. The Data: Analysis of 56.5 million U.S. hospital admissions (2000–2014) revealed a 12% higher risk of hospitalization for dementia with Lewy bodies in polluted areas. PM2.5 Exposure: Tiny airborne particles from traffic, factories, and wildfires were the main culprit. Animal Evidence: Mice exposed to PM2.5 develo...

Chocolate owes its irresistible taste to microbes at work

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Like wine and cheese, chocolate reflects its terroir — the soil, climate, and rainfall where it is grown. But much of chocolate’s unique flavor comes from microbes that ferment cocoa beans after harvest. These wild yeasts and bacteria shape whether a bar tastes floral, fruity, or more one-dimensional. From humble cocoa beans to rich chocolate, microbes work behind the scenes to unlock the flavors we love David Gopaulchan, a plant geneticist at the University of Nottingham, and colleagues studied cocoa fermentation on Colombian farms. By cataloging microbial communities and monitoring fermentation changes, they discovered how yeasts such as Saccharomyces cerevisiae kickstart the process by breaking down sugars into alcohol, raising bean temperature. This heat is crucial to kill the beans and prevent germination. Within 48 hours, bacteria like acetic acid– and lactic acid–producers transform alcohol into acids, further breaking down the pulp and releasing flavor precursors. Additional ...